Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
产品名称： Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
英文名称： Recombinant Biotinylated Human GPNMB Protein,His-Avi Tag
产品编号： 94051ES
产品价格： 询价
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2026-02-10T16:59:54
使用范围： null
翌圣生物科技（上海）股份有限公司
- 联系人 : 李自转
- 地址 : 上海市浦东新区天雄路166弄一号楼三层南单元
- 邮编 : 200030
- 所在区域 : 上海
- 电话 : 139****5640 点击查看
- 传真 : 点击查看
- 邮箱 : lizizhuan@yeasen.com
- 二维码 : 点击查看
产品介绍
GPNMB (Glycoprotein Nonmetastatic B) is a transmembrane glycoprotein encoded by the human gene GPNMB, belonging to the immunoglobulin superfamily. Below is a detailed introduction to the GPNMB protein.
GPNMB is involved in interactions between cells, promoting cell adhesion and migration, which is particularly important in embryonic development and tissue repair. As a cell surface antigen, GPNMB plays a crucial role in regulating immune responses. It can influence macrophage polarization and modulate inflammatory responses. GPNMB has been found to be highly expressed in various cancers, such as melanoma, breast cancer, and lung cancer. Research indicates that it may contribute to tumor progression by promoting the survival, proliferation, and metastasis of tumor cells.
Research on the GPNMB protein is ongoing, with the scientific community exploring its roles in various biological processes and its potential as a therapeutic target for diseases. Moreover, advancements in technology (such as single-cell RNA sequencing and high-throughput screening) provide new opportunities for a deeper understanding of GPNMB's functions and regulation.
产品性质
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产品别称
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GPNMB,HGFIN,NMB,Osteoactivin
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种属
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Human
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表达序列
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Ala 22 - Pro 486
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Accession
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AAH32783
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标签
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C-His-Avi Tag
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表达系统
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HEK293
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分子量
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The protein has a predicted MW of 53.7 kDa
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纯度
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> 95% as determined by SDS-PAGE
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内毒素
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< 1.0 EU per μg by the LAL method.
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制剂
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外观
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Liquid
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生物活性
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ELISA:Biotinylated Human GPNMB Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-GPNMB hlgG2 Antibody were added.
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产品特色
高纯度、高活性、低内毒素、高批间一致性
应用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Biotinylated Human GPNMB Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-GPNMB hlgG2 Antibody were added.
存储条件
-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。