SCF protein (Stem Cell Factor), also known as Kit Ligand-1 (KL-1), is a multifunctional cytokine protein that plays an important role in biological processes such as cell proliferation, differentiation, and survival. The SCF protein primarily exerts its effects by binding to its receptor c-Kit. c-Kit is a tyrosine kinase receptor that is widely expressed in various cell types. The binding of SCF to c-Kit activates multiple signaling pathways, including PI3K/Akt, MAPK, STAT, etc., thereby regulating cell growth, proliferation, and differentiation.

SCF protein plays a crucial role in the hematopoietic system, particularly in the proliferation and differentiation of stem cells. In diseases, SCF protein also plays a significant role. Aberrant activation of the SCF/c-Kit signaling pathway may lead to the development of certain diseases, such as tumors. Therefore, SCF protein and its receptor c-Kit could potentially serve as therapeutic targets for certain diseases.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA

Figure 2. Biotinylated Human SCF Protein,His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Human c-Kit(CD117) Protein; hFc Tag were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。